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NSAIDs Meaning in Medical

Author: Analgesia logo

Last Updated on October 7, 2025 by Analgesia team

NSAIDs Medical Abbreviation

In medical terms, the meaning of NSAIDs refers to nonsteroidal anti-inflammatory drugs, a class of medications commonly used to relieve pain, reduce inflammation, and lower fever. The meaning behind the term highlights the way these drugs work — unlike steroids, NSAIDs reduce inflammation by blocking enzymes (COX-1 and COX-2) involved in the body’s inflammatory process.

This makes them a core treatment option for conditions like arthritis, muscle strain, headaches, and menstrual pain. They can be used to treat a variety of conditions, including:

  • Muscle pain
  • Dysmenorrhea
  • Arthritis
  • Migraines
  • Headaches
  • Sprains and strains
  • Colds and flu
  • Coronavirus (COVID-19)

Some examples of NSAIDs include

Side Effects

NSAIDs can have serious side effects, including bleeding and problems with the stomach, kidneys, or heart. Research suggests that NSAIDs can also slow down the body’s natural healing process.

Common side effects
    • Gastrointestinal issuesStomach pain, indigestion, nausea, vomiting, diarrhoea, constipation, gas, and bloating
    • HeadachesHeadaches and dizziness
    • DrowsinessDrowsiness and feeling faint
    • High blood pressureNSAIDs can raise blood pressure in some people
    • Allergic reactionsSwollen lips, mouth, throat, or tongue, difficulty breathing, and skin, tongue, or lips turning blue, gray, or pale 

Serious side effects 

  • Stomach ulcersCan cause internal bleeding and anaemia
  • Heart problemsHeart failure, heart attacks, and strokes
  • Kidney problemsBlood in your urine, passing less urine, or feeling sick
  • Liver problemsJaundice or inflammation of the liver
  • AnaemiaFeeling faint, tired, or short of breath
  • Pancreas inflammationHigh temperature, stomach pain, and being sick
It should be used at the lowest effective dose for the shortest possible duration, and ideally under medical supervision, especially for those with underlying health conditions.

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