Last Updated on October 17, 2025 by Analgesia team
What is COPD
COPD is the medical abbreviation for chronic obstructive pulmonary disease.
- Chronic bronchitis: A long-term cough with mucus
- Emphysema: Damage to the lungs over time
Main causes of chronic obstructive pulmonary disease (COPD)
Chronic obstructive pulmonary disease, or COPD, is a long-term lung condition that makes it hard to breathe. The disease develops slowly and is often caused by years of exposure to harmful substances that damage the lungs. The main causes are tobacco smoking, air pollution, and genetic abnormalities.
1. Tobacco smoking
Tobacco smoke is the leading cause of COPD, responsible for the majority of cases worldwide. Studies show that three out of four people with COPD either currently smoke or have smoked in the past.
When cigarette smoke enters the lungs, it irritates and inflames the airways. Over time, this constant irritation destroys tiny air sacs called alveoli, reducing the lungs’ ability to exchange oxygen efficiently. The damage is permanent and tends to worsen even after quitting if the disease has already developed.
People with a family history of COPD face a higher risk. Smoking in such individuals acts as a trigger, speeding up the decline in lung function compared to non-smokers.
2. Air pollution
Air pollution is another significant factor, especially for people who live in densely populated cities or spend time near industrial areas. Long-term exposure to airborne toxins—such as dust, chemical fumes, and exhaust gases—can inflame and narrow the airways over time.
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Indoor pollution: In many homes, particularly in low-income regions, people cook or heat their homes by burning wood, charcoal, or other biomass fuels. The smoke from these materials contains fine particles and carbon monoxide, both of which can severely damage the lungs when inhaled daily.
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Outdoor pollution: Continuous exposure to particulate matter (PM2.5) and nitrogen dioxide (NO₂)—tiny particles from vehicle emissions and industrial waste—has been linked to reduced lung capacity and a higher risk of developing COPD, even in non-smokers.
Although air pollution alone may not cause COPD, it can worsen symptoms in those already diagnosed and increase the likelihood of developing the disease when combined with smoking.
3. Genetic abnormalities
In rare cases, COPD can occur due to a genetic condition rather than environmental exposure. The most recognised form is alpha-1 antitrypsin deficiency (AATD).
People with this inherited disorder have abnormally low levels of alpha-1 antitrypsin, a blood protein that protects the lungs from enzyme damage during inflammation. Without enough of this protein, the lung tissue breaks down more quickly, leading to early-onset emphysema—a major type of COPD—even in individuals who have never smoked.
If COPD is diagnosed in someone under 45 years old, or if there’s a strong family history of the disease, doctors often test for AATD to confirm or rule out a genetic cause.
In summary
Most cases of COPD are preventable. Quitting smoking, reducing air pollution exposure, and identifying genetic risks early can dramatically lower the likelihood of developing this chronic lung disease. Protecting your lungs today means breathing easier for years to come.
Treatment
There is no cure for COPD, but treatments can help slow its progression and keep it under control. Treatments include medicines, oxygen, pulmonary rehabilitation, and avoiding smoking and exposure to air pollution. We also have a detailed treatment for IE-COPD in our post IE-COPD medical abbreviation: What It Means & How It’s Managed.
COPD Pain Management
Pain management for chronic obstructive pulmonary disease (COPD) can include over-the-counter and prescription medications, heat therapy, massage, and lifestyle changes.
- Nonsteroidal anti-inflammatory drugs (NSAIDs): Such as ibuprofen (Advil) or aspirin, these can help with mild pain
- Opioids: Such as morphine or codeine, these can help with severe pain, but should be used with caution
- Mucolytic medicines: Such as carbocisteine or acetylcysteine, these can help with a chesty cough and thick phlegm
- Steroid tablets: These can help with flare-ups, but long-term use can cause side effects
- Heating pads: These can help with muscle and joint stiffness
- This can help with pain, muscle relaxation, and stress reduction
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Diet
Eating smaller meals more often, and choosing unprocessed foods like fish, lean meat, grains, fruits, and vegetables can help with pain
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Exercise
Cardio, stretching, and strengthening activities can help with breathing and muscle maintenance
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Palliative careThis can provide support for physical, emotional, spiritual, social, and respite care needs
Complications
COPD can lead to life-threatening problems. It’s important to plan for end-of-life care, such as palliative care, in advance.
COPD is sometimes called emphysema or chronic bronchitis. Emphysema is a form of COPD that damages the walls between the air sacs in the lungs, making it harder to move air out of the body. Chronic bronchitis is another form of COPD that involves a long-term cough with mucus
- Cigar smoke
- Secondhand smoke
- Pipe smoke
- Air pollution
- Workplace exposure to dust, smoke, or fumes