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Tramadol pain medicine

Tramadol Pain Medicine

Author: Analgesia logo

Last Updated on March 31, 2025 by Analgesia team

Tramadol is a prescription painkiller used to manage arthritis pain and other types of pain. It’s an opioid medication that works by changing the way your brain perceives pain. Opioids bind to specific receptors in the brain, spinal cord, and other body parts. These receptors are known as opioid receptors and are part of the body’s pain control system. When opioids attach to these receptors, they block the transmission of pain signals to the brain and alter the perception of pain.

Tramadol pain medicine

Opioids can also trigger the release of dopamine, a neurotransmitter associated with pleasure and reward, leading to feelings of euphoria and relaxation. This is the key factor that leads to addiction among its users.

Tramadol is primarily used for managing moderate to severe pain, including:

It is sold under the brand names Ultram®, Ultracet and Ultram® ER (extended release), among others.

Tramadol typically begins to work within one hour.

A recent guideline from the American Geriatrics Society recommends that all older patients with moderate to severe OA pain or diminished quality of life be considered for opioid therapy such as tramadol, because the risks of NSAIDs in these patients, including cardiovascular risk and gastrointestinal toxicity, may be serious enough to outweigh the potential for addiction.

Yes, Tramadol can be purchased online, but it is important to follow legal and ethical guidelines. In many countries, including the UK, Tramadol is classified as a controlled substance, meaning it requires a prescription from a licensed healthcare provider. Buying it without a prescription or from unverified sources can be illegal and unsafe

To buy Tramadol online in the UK, you must follow legal and safe practices. Tramadol is a controlled substance, so a valid prescription from a licensed healthcare provider is required. Here are some steps and options:

  1. Consultation: Many online pharmacies offer free consultations with licensed healthcare professionals to assess your need for Tramadol.
  2. Reputable pharmacies: Look for trusted UK-based online pharmacies that comply with regulations. Examples include:
    • My Pharmacy UK: Offers pain relief medications with a free online consultation.
    • Sleepy Pills: Provides Tramadol 50mg capsules with secure online ordering.
  3. Delivery: These pharmacies often provide discreet and fast delivery options, ensuring your medication arrives safely.

No, Tramadol is not an NSAID (Non-Steroidal Anti-Inflammatory Drug). It is a synthetic opioid analgesic used for pain relief. Unlike NSAIDs, which reduce inflammation, Tramadol works by altering pain perception in the brain and nervous system.

Tramadol is also not associated with kidney problems, unlike some other OA medications.

Tramadol provides several benefits when used appropriately and under medical supervision. Here are its key advantages:

  • Effective pain relief: It is highly effective for managing moderate to severe pain, such as post-surgical or chronic pain.
  • Central action: Unlike NSAIDs, it works directly on the nervous system to alter pain perception.
  • Versatile use: Available in various forms, such as tablets, capsules, and injections, catering to different patient needs.
  • Improved quality of life: By managing pain, it allows individuals to maintain mobility and engage in daily activities more comfortably.
  • Combination therapy: Can be paired with other pain relief medications for enhanced effects.
  • Pain Relief: Tramadol helps alleviate moderate to severe pain by binding to opioid receptors in the brain.
  • Non-NSAID Option: Unlike NSAIDs (e.g., ibuprofen), tramadol does not cause stomach or kidney issues.
  • Dosage: Tramadol comes in various forms, including tablets, capsules, drops, and injections. The dosage and frequency depend on the severity of the pain and individual response.
  • Administration: It’s important to follow your doctor’s instructions on how to take tramadol, as it can be addictive.
  • Pain Reduction: Studies have shown that tramadol can reduce pain by about 4 points on a 0-100 scale compared to a placebo. A placebo is anything that seems to be a “real” medical treatment but isn’t. It could be a pill, a shot, or some other type of “fake.
  • Physical Function: It can also improve physical function by about 4% compared to a placebo.
  • Common Side Effects: Nausea, vomiting, dizziness, constipation, tiredness, and headache.
  • Serious Side Effects: There is a risk of dependence and other serious side effects, so it should be used under medical supervision. Recently, Arthritis Research Canada has found that people with osteoarthritis who started taking tramadol were at a 20-50 percent greater risk of mortality, 70 percent greater risk of blood clots, and 40-60 percent greater risk of hip fractures when compared to people who started using drugs like aspirin or ibuprofen.

Reducing the side effects of tramadol involves several strategies and careful management. Here are some tips:

  • Dosage: Take the prescribed dose and avoid self-adjusting the medication.
  • Timing: Stick to the recommended schedule to prevent withdrawal symptoms and manage pain effectively.
  • Fluid Intake: Drink plenty of water to help prevent constipation, a common side effect of opioids.
  • High-Fiber Diet: Include plenty of fruits, vegetables, and whole grains in your diet to promote regular bowel movements.
  • Fiber Supplements: Consider fiber supplements if dietary changes are not enough.
  • Physical Activity: Engage in regular physical activity to help with bowel movements and overall well-being.
  • Stool Softeners: Over-the-counter stool softeners can help alleviate constipation.
  • Prescription Medications: Your doctor may prescribe medications to manage constipation if it becomes a significant issue.
  • Report Issues: Inform your doctor if you experience severe side effects like severe constipation, dizziness, or difficulty breathing.
  • Tapering Off: If you need to stop taking tramadol, your doctor will likely recommend a gradual reduction to minimize withdrawal symptoms.
  • Non-Opioid Medications: Use over-the-counter pain relievers like acetaminophen or NSAIDs when appropriate.
  • Non-Pharmacological Methods: Consider physical therapy, acupuncture, massage, and other non-drug therapies.
  • Counseling: Seek support from a mental health professional to manage anxiety or depression that may arise from chronic pain or opioid use.

By combining these strategies, you can effectively manage and reduce the side effects of tramadol. Always consult with your healthcare provider for personalized advice and guidance.

Tramadol is classified as a Schedule 3 Controlled Drug in many regions, including the UK. This means:

  • Prescription requirements: It must be prescribed by a licensed healthcare provider.
  • Storage and handling: Strict regulations govern its storage and dispensing to prevent misuse.
  • Usage limitations: Prescriptions are typically valid for 28 days, with restrictions on the quantity dispensed.

Useful Resource

Arthritis Society Canada | Tramadol
Cochrane | Tramadol for osteoarthritis
Arthritis Connection | Tramadol Medication for Arthritis- What You Need to Know
Arthritis Research Canada | New Research Ties Popular Pain Killer to Serious Health Risks 
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