SCF

Last Updated on December 22, 2024 by Analgesia team

SCF Medical Abbreviation

SCF is a medical abbreviation for stem cell factor, a growth factor and cytokine that helps blood stem cells develop into different types of blood cells: 

Function

SCF stimulates the survival, proliferation, and differentiation of hematopoietic cells. It’s also important for the production and function of mast cells and for developing melanocytes, germ cells, and intestinal pacemaker cells. 

Other names

SCF is also known as kit ligand (KL), mast cell growth factor (MCGF), or steel (Sl) factor (SLF). 

How it works

SCF binds to and activates the c-kit receptor tyrosine kinase, a cell surface receptor. 

Potential therapeutic use

SCF and granulocyte colony-stimulating factor (G-CSF) have shown potential to help repair the brain after a traumatic brain injury (TBI). 

SCF may also refer to supraclavicular fossa node, which can be the subject of a biopsy. 

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