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what does HIV/AIDS pain feel like

HIV and Pain

Author: Analgesia logo

Last Updated on March 3, 2025 by Analgesia team

Pain is common for people living with HIV/AIDS, and can have many causes. 

Causes 

  • HIV itself: The virus can cause inflammation and nerve damage
  • Medications: Some HIV medications can be neurotoxic
  • Immune response: The body’s immune response to HIV can cause inflammation
  • Secondary complications: Cancers and infections can cause pain
  • Aging: Pain becomes more common as people with HIV age

Types of pain 

  • Painful neuropathy in the hands and feet
  • Headaches
  • Pain in the mouth, throat, abdomen, chest, and anus
  • Joint and muscle pain
  • Painful skin conditions
  • Pain from Kaposi’s sarcoma

Management 

  • Non-drug therapies like massage, acupuncture, meditation, and exercise can help manage pain
  • Heat or cold therapy can help with pain
  • Anti-inflammatory diet
  • Talk therapies
  • Joining a chronic pain support group

Other considerations

  • Pain can be widespread and affect multiple parts of the body 
  • Pain can be difficult to manage 
  • HIV-positive women may experience pain more frequently and more intensely than men 
  • The risk of opioid misuse is elevated in the HIV-infected population 

HIV pain can feel like muscle and joint aches, nerve pain, headaches, and abdominal pain. 

  • Achy muscles and joints are common early symptoms of HIV
  • Peripheral neuropathy is nerve damage that can cause numbness, tingling, or burning. It usually affects the feet and hands but can also affect the arms and legs.
  • Headaches can be a common side effect of HIV drugs. They can feel like pressure, throbbing, or a dull ache.
  • HIV drugs can cause nausea, diarrhea, and stomach cramps. These symptoms often go away in a few days or weeks.
  • Back pain can occur in the early stages of HIV

Other HIV symptoms 

  • Sore throat,
  • Body rash,
  • Tiredness,
  • Swollen glands,
  • Mouth sores, and
  • Fever.

Even when HIV is suppressed to undetectable levels, people can still develop pain. 

Causes of HIV-related pain 

  • Inflammation of the pancreas
  • HIV itself

HIV drugs

  • Other medical conditions such as diabetes
  • Infections caused by bacteria or parasites
  • Problems of the digestive tract

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