Last Updated on December 15, 2024 by Analgesia team
PRCA Medical Abbreviation
PRCA is a medical abbreviation for pure red cell aplasia, a rare blood disorder that causes anemia by reducing the bone marrow’s production of red blood cells:
Pure red cell aplasia (PRCA) |
|
|---|---|
What it is |
A rare blood disorder that causes anemia by reducing the bone marrow’s production of red blood cells
|
Causes |
The causes can be congenital or acquired and may be associated with various underlying causes, such as autoimmune diseases, viral infections, or exposure to certain medications or toxins
|
Symptoms |
Defined by persistent anemia, reticulocytopenia, and a bone marrow devoid of erythroid precursors
|
Treatment |
Typically involves immunosuppression, but specific pathogenic subtypes are associated with specific therapeutic approaches
|
PRCA can be a complication of major or bidirectional ABO-incompatible allogeneic hematopoietic stem cell transplants (allo-HSCT). It can also be associated with collagen vascular/autoimmune disorders such as systemic lupus erythematosus, lymphoproliferative disorders such as chronic lymphocytic leukemia or large granular lymphocyte leukemia, infections, particularly B19 parvovirus, thymoma and other solid tumors.